David Sinclair Supplements (2020) | TOP Brands for Anti-Aging!

The question ‘what supplements David Sinclair is taking’ is best left for a non-scientific website (statistical analyses are outside the scope of this blog post). In case you’re interested, here are the supplements that he is taking. If you read through the supplements and are interested in adding some extra information, you can send me an email.

What Supplements David Sinclair is taking?


Lecithin is an emulsifier found in many types of dietary supplements? It is a complex blend of fatty acids and complex polysaccharides that, when present in low concentrations, prevents the destruction of fat-soluble vitamins, especially vitamin E. As pointed out in this detailed guide here about David Sinclair Supplements:  “Lecithin promotes the production of important proteins” It is commonly found in high protein dairy products, gelatin, casein, egg yolks, and chocolate and is also a good source of choline. Lecithin’s benefit was noted to be superior to that of other nutritionists when they conducted a study with more than 700 patients with heart failure who were placed on a diet similar to the Weston A. Price Foundation High Protein Diet. Those on the Lecithin diet had significantly higher blood levels of HDL cholesterol. Many of the study subjects said that their symptoms had been reduced significantly during the dietary intervention. Many recommended the Lecithin diet and others were able to reduce their risk of heart failure.

Burroughs Wellcome Advanced Nutrition Lifesaver, Folate – is a B vitamin that assists in the action of six enzymes involved in the synthesis of the amino acids leucine, valine, isoleucine, threonine, and histidine. It also contributes to the development of both red blood cells and the glycoproteins that serve as their transport system. This nutrient plays an important role in the ability of the body to metabolize fats and glycogen into glucose. [Summary from wikipedia]


Leucine is a B vitamin and a component of proteins that aids in the action of 6 of the essential amino acids, arginine, glutamine, methionine, phenylalanine, and tryptophan. Leucine assists in the degradation of both amino acids and amino hydrolysates, and is required for the generation of energy from ATP, such as from glucose or lactate. Leucine is also required for the transmission of messages between cell nuclei and mitochondria, especially when energy or nutrient levels are low. Leucine is essential for protein synthesis and helps to regulate protein turnover. It also plays an important role in the treatment of insulin resistance, inflammation, and gallstones. There is good evidence that deficiency of dietary protein contributes to muscle wasting, bone loss, and cognitive impairment, which all are considered major risk factors for Alzheimer’s disease (AD). Interestingly, the genetic factors associated with protein metabolism have been implicated in the development of AD. [More information from Yahoo!]


contains minerals and is linked to a heart-healthy diet that increases the body’s ability to utilize vitamin D. Vitamin D is important in many body functions and must be obtained through the diet. However, for various reasons, a deficiency is also common in this population. Low intake may be due to the high cost of vitamin D or other factors that may occur in low-income areas.

Vitamin B6

Vitamin B6  is found in animal products. These include egg yolks, milk, and cereal. B vitamins are important for the metabolism of fats and proteins, the formation of DNA, and for the conversion of compounds like glucuronic acid (with normal amounts in animal products) into cholesterol and bile acids.

Folic Acid

Folic Acid – is a B vitamin and helps the body to synthesize important proteins. It is often added to fortified foods and in tea to help prevent neural tube defects.


Calcium – is a mineral required for the formation of the skeleton, the relaxation of arteries, and bone growth. It also plays an important role in an enzyme called renin, which controls blood pressure. It is found in all foods that have bones. Like all nutrients, it is beneficial to include calcium in the diet to help maintain strong bones, teeth, nerves, and muscles.


Iron – helps produce the important red blood cells that carry oxygen to the body and the muscles. Iron plays an important role in the production of amino acids, including acetyl-CoA, creatine, and dopamine. Iron is needed to create new red blood cells and new red blood cells will die if there is not enough iron available for them to perform their important functions.


Zinc – is an essential mineral that helps the body process and uses essential fatty acids like linoleic acid. It also helps generate the enzymes that break down waste products, such as lactic acid. However, zinc and other minerals must be consumed daily in large amounts and in foods fortified with this mineral to attain their maximum benefit.


Magnesium – is a trace mineral that is necessary for normal nerve function, muscle function, and the central nervous system. It also helps to protect the heart, lungs, and blood vessels from damage caused by the toxins and hormones that are produced by the body. It is found in green vegetables, beans, nuts, and many nuts and seeds.

David Sinclair is a passionate yogi. He’s also the author of the best-selling book, Optimal Performance for the Sports Science Kind of Guy, and he’s a regular contributor to my blog.

In the book, David takes readers on a journey on how to become a better human. He shares some great insights on productivity, stress, and sleep. In the two years since the book was published, it’s risen to become one of my top-selling books.

What are NMN Supplements: Dosage& Benefits?

N-methyl-N-nitrosourea (NMN), also called N-methyl-N’-nitrosourea (NMN), is a chemical compound created by bacteria, plants, and viruses. It’s also called the third nitrate in the C5 chemical pathway, after nitrate and nitrite.

The NMN pathway is used in the synthesis of most of the compounds used by people to stay healthy. It’s also important for maintaining muscle, nerve, bone, and ligament strength, controlling blood sugar levels, and regulating your nervous system.

It works best when you take supplements and foods with NMN at the same time. It’s also important to take them in large amounts over the course of a day.

How to Take NMN Supplements’

You can take up to a daily serving of nitrate-rich foods or supplements with NMN along with your meals. Be sure to avoid taking it during times when you’re tired and in need of rest. The recommended amounts are shown in our Supplements for Bone Health List.

Gives you a boost to your metabolism, boosts your nervous system, and also helps you regain and build your muscle mass.

What is NAD+ and Why is it Important?

NAD+ is a 2-carbon monoglucoside molecule that is often referred to as NAD+ or nicotinamide mononucleotide. It is the only vitamin that is derived directly from plant-based food. It can be found in red meat (beef), poultry, fish, and poultry (chicken, turkey, duck, and lamb). It is found in high amounts in red meat and the higher the level of the meat and the higher the percentage of meat, the more NAD+ that will be produced.

NAD+ in the Blood is Controlled by 2 Molecules

In your liver, NAD+ is converted to NADH through enzyme-catalyzed reactions called the Krebs cycle. The conversion is tightly controlled by the activity of an enzyme called Sirt1. Sirt1 is a deacetylase that produces NADH. The Sirt1 enzyme has two forms: NADH (sirtuin 1-deacetylase) and NAD+ (sirtuin 1-deacetylase). Sirt1 is an enzyme that is tightly regulated by the activity of a complex called the NAD+ (nicotinamide mononucleotide) coenzyme A (NMN) coenzyme complex.

What Doesn’t David Sinclair Eat and Supplement?

David Sinclair eats a varied diet with plenty of vegetables, nuts, fish, and high-quality proteins. His personal regimen consists of lots of high-intensity strength and conditioning training (including squats and bicep curls), lots of high-intensity, consistent exercise (including skiing, biking, and ultramarathoning), and lots of eating. He also drinks lots of water.

David Sinclair is an overall healthy guy, but he never drinks alcohol and he was never on drugs. He does, however, enjoy or do some amount of alcohol occasionally.

He’s also willing to do a few supplements. In 2010, he wrote a blog post about how he helps to keep himself healthy while being a team member at the New York Giants (see “Do You Eat Sports Science Stuff?”).

Last year, a series of videos on David’s fitness journey was released, which you can find here.

Where Did David Sinclair Get His Nutrition Advice and Training Tips?

In “Do You Eat Sports Science Stuff?” David writes about one of his favorite fitness tips from Dr. Chip Carroll. Dr. Carroll used to be the VP of Science for Nike, and he provides amazing advice on nutrition and training.

In “Nutrition Tip #1”: eat fat when you can

“Dr. Carroll would tell you that the best fuel for intense exercise is fat. … Here’s the deal: Most people think they can eat anything. They think they can eat ice cream, they think they can eat vegetables, they think they can eat fat … we’re not meant to eat chocolate, we’re not meant to eat ice cream. There’s fat in it. Some people think it’s essential, essential to athletic performance. … For fast, we don’t get the insulin spike of carbohydrate; so when you eat fat, your blood sugar will go up and you will get a spike in your oxygen consumption; your body fat will burn off.”

Dr. Carroll has a fair amount of scientific backing for his opinion on this. While he’s no nutritionist, the research does back up his assertion that when you eat fat, you’ll be able to maximize your performance. On top of that, David has a knack for finding answers to things in the books that aren’t that common. In this case, he finds nutrition information that’s actually being put into practice by athletes.

For example, in this talk he goes over Nutrition 101: A-Z from a world-class swimmer:

I wanted to get Dr. Carroll’s back story on that talk, so I approached him about my questions.

Here’s what Dr. Carroll had to say:

“When I write about nutrition, and you read my book and you watch my videos, I tell you what I’ve learned from 20 years of training and coaching. A lot of it I learned on my own; a lot of it was from my family and friends, through conversations.

When I was a swimmer, I had a trainer who would give me ideas every week. He used to say to me, “Every time you eat, you’re getting the equivalent of a second workout.” I was one of the first people in the world to understand this; they didn’t want me to feel sluggish.

He’d say, “When you eat, you burn a gallon of oxygen per day.” This is what happens when you drink lots of water. … My trainer would make me eat two pounds of red meat and two pounds of fish and I would explode with an explosion of energy. I would go the week after eating that, I would not be the athlete I was.”

So David can read this stuff and see why athletes are following this lifestyle. So I asked Dr. Carroll if he knew anything about the scientific research that backs up this research. Here’s what he had to say: “Well, I’m a believer in something called kinetics. …

When you eat, your body releases energy at the fastest rate it can. You are getting more of a rate of energy release than you are burning at the rate of energy release.”

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